Drug Therapy

  • Does my patient need an allergy evaluation for penicillin allergy?
    Jennifer A. Ohtola, MD, PhD and Sandra J. Hong, MD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 126-129; DOI: https://doi.org/10.3949/ccjm.89a.21004

    In patients with reported penicillin allergy, obtaining a detailed allergy history directly from the patient is the essential first step.

  • Breast cancer risk evaluation for the primary care physician
    Christine L. Klassen, MD, Elizabeth Gilman, MD, Aparna Kaur, MD, Sara P. Lester, MD and Sandhya Pruthi, MD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 139-146; DOI: https://doi.org/10.3949/ccjm.89a.21023

    The authors offer a systematic approach to the assessment and management of patients at risk of breast cancer.

  • Stellate ganglion block as a treatment for vasomotor symptoms: Clinical application
    Stellate ganglion block as a treatment for vasomotor symptoms: Clinical application
    Yeonsoo Sara Lee, BS, Christopher Wie, MD, Scott Pew, MD and Juliana M. Kling, MD, MPH
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 147-153; DOI: https://doi.org/10.3949/ccjm.89a.21032

    Hormone therapy is the mainstay of treatment, but there is a clear need for safe and effective nonhormonal options. The authors review data on the use of stellate ganglion block in perimenopausal and postmenopausal patients.

  • Vitamin D supplementation: Pearls for practicing clinicians
    Susan E. Williams, MS, RD, MD, CCD, FACE, FAND
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 154-160; DOI: https://doi.org/10.3949/ccjm.89a.21021

    A review of how to assess and counsel patients on the use of vitamin D, with patient scenarios clinicians are likely to encounter, and an overview of current recommendations for vitamin D supplementation.

  • Anaphylaxis: Highlights from the practice parameter update
    Katherine N. Weller, MD and Fred H. Hsieh, MD
    Cleveland Clinic Journal of Medicine February 2022, 89 (2) 106-111; DOI: https://doi.org/10.3949/ccjm.89a.21076

    The update addresses diagnostic criteria, treatment options, prevention of recurrences, and patient education on avoiding triggers and using self-injectable epinephrine.

  • Anaphylaxis: Expanding our perspective
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2022, 89 (2) 65; DOI: https://doi.org/10.3949/ccjm.89b.02022

    Anaphylaxis is not always the extreme scenario we learned about in medical school. There is a range of far milder allergic infusion reactions that are nonetheless anaphylaxis.

  • Hypertrichosis and topical corticosteroid use
    Yuya Ando, MD, Sachiko Ono, MPH, PhD, Yosuke Ono, MD, PhD and Yoshinori Miura, MD, PhD
    Cleveland Clinic Journal of Medicine February 2022, 89 (2) 71-72; DOI: https://doi.org/10.3949/ccjm.89a.21048

    The xerotic dermatitis had resolved 2 years earlier, but the patient had continued to apply the medication.

  • Extraosseous calcification in kidney disease
    Extraosseous calcification in kidney disease
    Korey Bartolomeo, DO, Xin Yee Tan, MD and Richard Fatica, MD
    Cleveland Clinic Journal of Medicine February 2022, 89 (2) 81-90; DOI: https://doi.org/10.3949/ccjm.89a.21073

    A review of the pathogenesis, presentation, diagnosis, and treatment of vascular and soft tissue calcifi cation.

  • Hypercalcemia and vitamin A: A vitamin to keep in mind
    Saif Munther Borgan, MD, Leila Zeinab Khan, MD and Vinni Makin, MD, FACE
    Cleveland Clinic Journal of Medicine February 2022, 89 (2) 99-105; DOI: https://doi.org/10.3949/ccjm.89a.21056

    Vitamin A toxicity can affect bone resorption and hypercalcemia and should be explored in unexplained cases of parathyroid hormone-independent hypercalcemia.

  • Clinical impact of 2020 American Heart Association statement on menopause and cardiovascular disease risk
    Tara K. Iyer, MD, NCMP and Heather Hirsch, MD, MS, NCMP
    Cleveland Clinic Journal of Medicine January 2022, 89 (1) 13-17; DOI: https://doi.org/10.3949/ccjm.89a.21031

    The statement supports the notion that the transition of menopause itself leads to increased cardiovascular risk and mortality.

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