Drug Therapy

  • Drugs that may harm bone: Mitigating the risk
    Faye N. Hant, DO, MSCR and Marcy B. Bolster, MD
    Cleveland Clinic Journal of Medicine April 2016, 83 (4) 281-288; DOI: https://doi.org/10.3949/ccjm.83a.15066

    The implicated drugs have important therapeutic roles, so their benefits must be weighed against the risks.

  • Managing diabetes in hospitalized patients with chronic kidney disease
    Shridhar N. Iyer, MD, PhD, FACP and Robert J. Tanenberg, MD, FACP
    Cleveland Clinic Journal of Medicine April 2016, 83 (4) 301-310; DOI: https://doi.org/10.3949/ccjm.83a.14189

    Avoiding hypoglycemia takes precedence over meeting strict blood sugar targets.

  • In reply: The PARADIGM-HF trial (October 2015)
    Marwa A. Sabe, MD, MPH, Miriam S. Jacob, MD and David O. Taylor, MD
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 167-168; DOI: https://doi.org/10.3949/ccjm.83c.03002
  • The PARADIGM-HF trial (October 2015)
    Robert P. Blankfield, MD, MS
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 167; DOI: https://doi.org/10.3949/ccjm.83c.03001

    A reader comments on the fi ndings of the PARADIGM-HF trial (October 2015).

  • Can patients with infectious endocarditis be safely anticoagulated?
    Mandeep Singh Randhawa, MD, James Pile, MD and Marcelo Gomes, MD
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 169-171; DOI: https://doi.org/10.3949/ccjm.83a.15027

    New infectious endocarditis is not an indication for starting anticoagulation, and whether to continue it is a diffi cult decision.

  • Fungal folliculitis masquerading as acute exanthematous pustulosis
    Timmie Sharma, MD, Alok Vij, MD and Apra Sood, MD
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 179-180; DOI: https://doi.org/10.3949/ccjm.83a.15028

    Concern was raised for antibiotic-related acute exanthematous pustulosis, but punch biopsy revealed the yeast Malassezia.

  • Advances in the treatment of dyslipidemia
    Marc S. Sabatine, MD, MPH
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 181-186; DOI: https://doi.org/10.3949/ccjm.83gr.16001

    Current guidelines do not set specifi c targets for LDL-C, but evidence supports the concept that lower is better.

  • Prescribing opioids in primary care: Safely starting, monitoring, and stopping
    Daniel G. Tobin, MD, FACP, Rebecca Andrews, MD, FACP and William C. Becker, MD
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 207-215; DOI: https://doi.org/10.3949/ccjm.83a.15034

    Prescription drug abuse has reached epidemic proportions. Some patients benefi t from opioids, but many suffer harm.

  • Common neurologic emergencies for nonneurologists: When minutes count
    Mohan Kottapally, MD and S. Andrew Josephson, MD
    Cleveland Clinic Journal of Medicine February 2016, 83 (2) 116-126; DOI: https://doi.org/10.3949/ccjm.83a.14121

    Recognizing and treating acute stroke, status epilepticus, subarachnoid hemorrhage, and others.

  • Alcohol withdrawal syndrome in medical patients
    Justine S. Gortney, PharmD, BCPS, Joshua N. Raub, PharmD, BCPS, Pragnesh Patel, MD, Lianne Kokoska, PharmD, Mae Hannawa, PharmD and Amy Argyris, PharmD, BCPS
    Cleveland Clinic Journal of Medicine January 2016, 83 (1) 67-79; DOI: https://doi.org/10.3949/ccjm.83a.14061

    Deprived of alcohol while in the hospital, many alcoholic patients go into withdrawal. Clinicians should be ready.

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