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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Drug Therapy

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    Cardiac surveillance for anti-HER2 chemotherapy
    Patrick Collier, MD, PhD, FASE, FESC, FACC, Muzna Hussain, MD, Zoran B. Popovic, MD, PhD and Brian P. Griffin, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 110-116; DOI: https://doi.org/10.3949/ccjm.88a.19150

    A more focused approach is advocated.

  • Precision treatment for metastatic non–small cell lung cancer: A conceptual overview
    You have access
    Precision treatment for metastatic non–small cell lung cancer: A conceptual overview
    Tristan Lee, MD, Jeffrey M. Clarke, MD, Deepali Jain, MD, Sendhilnathan Ramalingam, MD and Vishal Vashistha, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 117-127; DOI: https://doi.org/10.3949/ccjm.88a.19148

    Targeted therapy has revolutionized treatment of patients with advanced solid tumors.

  • You have access
    How should you assess glycemic control if the hemoglobin A1c is inaccurate or uninterpretable?
    Wendy O. Henderson, MD, Mary H. Parker, PharmD, FASHP, FCCP, BCPS, BCCP and Bryan C. Batch, MD, MHS
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 81-85; DOI: https://doi.org/10.3949/ccjm.88a.19135

    Hemoglobin A1c is the standard but is not perfect. Alternatives are available.

  • You have access
    A 21-year-old woman with Ehlers-Danlos syndrome and persistent lightheadedness
    Raed Qarajeh, MD, Laith A. Derbas, MD, Mouin Abdallah, MD, MSc and Faraz Kureshi, MD, MSc
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 93-97; DOI: https://doi.org/10.3949/ccjm.88a.19137

    She has a long history of lightheadedness upon standing, and it is getting worse.

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    Reversal of direct oral anticoagulants: Highlights from the Anticoagulation Forum guideline
    Haeshik S. Gorr, MD, Lucy Yun Lu, PharmD, MS and Eric Hung, PharmD, CACP, AE-C
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 98-103; DOI: https://doi.org/10.3949/ccjm.88a.19133

    Clear instructions on how to manage DOAC-associated bleeding.

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    A patient with breast cancer and a rash on her hands and feet
    Jonathan Stewart, BS, Grace U. Salacup, MD and Kevin Bryan Uy Lo, MD
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 22-23; DOI: https://doi.org/10.3949/ccjm.88a.20020

    She had completed her third cycle of chemotherapy 3 days earlier.

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    Cryptosporidiosis in an immunosuppressed patient with persistent diarrhea
    Firas Bahdi, MD, Shilpa Jain, MD and Suneal Kumar Agarwal, MD, FACG
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 24-26; DOI: https://doi.org/10.3949/ccjm.88a.20016

    A 29-year-old lung transplant recipient presents with diarrhea lasting 1 month.

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    Prescribing testosterone and DHEA: The role of androgens in women
    Taryn Smith, MD, NCMP and Pelin Batur, MD, FACP, NCMP
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 35-43; DOI: https://doi.org/10.3949/ccjm.88a.20030

    Androgens play an important physiologic role and can promote sexual health.

  • You have access
    Trials and tribulations of testosterone therapy in women: Importance of adhering to the evidence
    Juliana M. Kling, MD, MPH, NCMP, FACP and Sharon J. Parish, MD
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 44-46; DOI: https://doi.org/10.3949/ccjm.88a.20195

    Testosterone should not be touted for outcomes that are not supported by data.

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    The role of SGLT-2 inhibitors in managing type 2 diabetes
    Yumiko Tsushima, MD, M. Cecilia Lansang, MD, MPH and Vinni Makin, MBBS, MD, FACE
    Cleveland Clinic Journal of Medicine January 2021, 88 (1) 47-58; DOI: https://doi.org/10.3949/ccjm.88a.20088

    These drugs improve glycemic control and offer cardiovascular and metabolic benefits.

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