Physical Exam
- Allopurinol hypersensitivity is rare, bad, and partially avoidable, but allopurinol can still be used effectively
The shadow of the 1984 Hande et al guidelines still hangs over clinical decision-making when managing allopurinol dosing in patients with gout and chronic kidney disease.
- Severe cutaneous reaction induced by allopurinol
Three weeks after starting allopurinol for gout, an 86-year-old woman presented with a maculopapular rash and painful blistering and erosions of the oral mucosa.
- Amoxicillin rash in infectious mononucleosis
A 23-year-old woman developed a rash on the day she completed a 10-day course of amoxicillin for group A streptococcal infection.
- What diagnostic tests should be done after discovering clubbing in a patient without cardiopulmonary symptoms?
Computed tomography of the patient’s chest is indicated based on the robust association between clubbing and intrathoracic malignancy.
- Vesicular pityriasis rosea
A 37-year-old man presented with a 9-day history of disseminated pruritic rash on his trunk and extremities.
- Oral condylomata lata
The patient had a 3-month history of painless oral lumps and intermittent sore throat.
- It’s time for a little history of medicine—introducing a new feature in CCJM
This month, we debut a feature focused on topics in the history of medicine, authored by Cleveland Clinic rheumatologist Adam Brown, MD.
- Skin manifestations in a patient with acute bacterial infective endocarditis
During a dialysis session, the patient experienced the onset of rigors accompanied by the appearance of painless purpuric lesions, which developed into petechiae.
- The history of blood cultures: From the research laboratory to the bedside
Efforts to prove that bacteria cause endocarditis paved the way for use of blood cultures in the clinic.
- Salt-and-pepper skin pigmentation
Dermoscopy of the skin lesions revealed homogeneous depigmented areas with perifollicular pigmentation.