Physical Exam

  • Widespread skin-thickening and hyperpigmentation
    India K. Poetzscher, Nikolai Klebanov, MD and Shinjita Das, MD, MPH
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 485-487; DOI: https://doi.org/10.3949/ccjm.89a.21099

    A 37-year-old military veteran presented with extensive velvety hyperpigmented plaques over nearly 15% of the total body surface.

  • Phenytoin-induced gingival overgrowth
    Mitesh Karn, Ranjan Sah and Shabal Sapkota, MD
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 488-489; DOI: https://doi.org/10.3949/ccjm.89a.21107

    A young man presented with lower-extremity weakness and slurred speech. He has been on seizure prophylaxis after experiencing a seizure following hemicraniectomy for subdural hematoma.

  • Nasal herpes simplex virus infection
    Nina L. Tamashunas, MD, Robert Simonds, MD and Sarah Young, MD
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 495-496; DOI: https://doi.org/10.3949/ccjm.89a.21096

    Skin changes on the nose in a 37-year-old patient that began after a scratch were concerning for extensive nasal skin necrosis.

  • Hyperpigmentation as a clue to Addison disease
    Yusuke Hirota, MD, PhD and Takaya Matsushita, MD, PhD
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 498-499; DOI: https://doi.org/10.3949/ccjm.89a.21082

    The 66-year-old woman presented with fatigue, loss of appetite, and hyperpigmentation of the tongue, soft palate, buccal mucosa, lower lip, fingers, and nail beds.

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