Latest Articles

  • What is a ‘failure’ of bisphosphonate therapy for osteoporosis?
    John J. Carey, MD
    Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1033-1039;

    Assessing the effectiveness of bisphosphonate therapy is problematic. The true measure is prevention of new fractures.

  • Influenza 2005–2006
    Sherif B. Mossad, MD
    Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1041-1047;

    Behind the preparation for the current influenza season are fears that the simmering outbreak of avian influenza in animals could lead to a pandemic in humans.

  • Hepatitis C infection: A systemic disease with extrahepatic manifestations
    Hepatitis C infection: A systemic disease with extrahepatic manifestations
    Aman Ali, MD and Nizar N. Zein, MD
    Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1005-1019;

    Almost 40% of patients with hepatitis C develop at least one extrahepatic manifestation during the course of the disease.

  • A 73-year-old woman with chronic nonhealing cellulitis
    Anthony K. Leung, DO and Wendy S. Armstrong, MD
    Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1022-1024;

    She has undergone extensive treatment with antibiotics and corticosteroids, without success. What is the likely diagnosis?

  • DHEA supplementation: The claims in perspective
    Ewa Olech, MD and Joan T. Merrill, MD
    Cleveland Clinic Journal of Medicine November 2005, 72 (11) 965-984;

    Low DHEA levels are seen in a variety of diseases, but whether supplemental DHEA will help remains unproven.

  • Pulmonary embolism imaging (SEPTEMBER 2005)
    Michael Emmett, MD and Joseph M. Rothstein, MD
    Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1059;
  • Safety of statins: Effects on muscle and the liver
    Abu R. Vasudevan, MBBS, MD, MRCP, Yasmin S. Hamirani, MBBS and Peter H. Jones, MD
    Cleveland Clinic Journal of Medicine November 2005, 72 (11) 990-1001;

    Hepatotoxicity and myopathy are uncommon but worrisome. ALT and AST should be measured at baseline and periodically during statin therapy.

  • In reply: Pulmonary embolism imaging (SEPTEMBER 2005)
    Ruffin J. Graham, MD and Joseph W. Stengel, MD
    Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1059;
  • Update in thrombosis: Answers to perplexing questions
    Daniel G. Federman, MD, Gina R. Brescia, MD, John P. Moriarty, MD, Sally G. Haskell, MD, Raj Krishnamurthy, MD and Robert S. Kirsner, MD, PhD
    Cleveland Clinic Journal of Medicine October 2005, 72 (10) 907-915;

    How long should patients receive warfarin? Is less-intense therapy as effective as standard therapy? When is the risk of recurrence highest? Do mutations increase the risk of recurrence?

  • Pleural effusions: Evaluation and management
    José C. Yataco, MD and Raed A. Dweik, MD
    Cleveland Clinic Journal of Medicine October 2005, 72 (10) 854-872;

    A rational diagnostic workup will reveal the cause in most cases.

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