Latest Articles
- Use of corticosteroids in the sepsis syndrome: What do we know now?
Although there is a physiologic rationale for using corticosteroids in sepsis, there are also safety concerns. A definitive trial is under way. This article analyzes the evidence to date and gives the authors personal recommendations.
- Dyslipidemia in HIV patients
HIV can raise lipid levels, and so do the drugs used to treat it. As patients with HIV infection live longer, these non-HIV medical problems become more relevant.
Renovascular hypertension: Balancing the controversies in diagnosis and treatmentWhich patients should undergo testing for renovascular hypertension, and with which test? What are the roles of renal angioplasty and stenting?
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- How long can my patient use intranasal steroid sprays?
There is little evidence to indicate they cause significant systemic side effects. However, patients who use them regularly should undergo examinations of the nasal cavity at least once a year to check for damage to the septum.
- Frailty in older adults: Insights and interventions
We are getting better at systematically predicting who is vulnerable and at understanding the biologic basis of this vulnerability, which should lead to interventions to improve outcomes.
- Safety of statins: Effects on muscle and the liver
Hepatotoxicity and myopathy are uncommon but worrisome. ALT and AST should be measured at baseline and periodically during statin therapy.
