Latest Articles
- Evaluating and managing hypogammaglobulinemia
Patients with frequent and recurrent respiratory infections should be tested for immune system abnormalities. This article describes common primary and secondary forms of hypogammaglobulinemia and how to evaluate and manage them.
- Natriuretic peptide testing: A window into the diagnosis and prognosis of heart failure
BNP assays are now widely used to evaluate suspected heart failure, but they should not be the only criterion.
- How should we advise patients about the contraceptive patch, given the FDA warning?
In theory, patients could face a higher risk of thromboembolism than with oral contraceptives. But most of all we want to urge them not to simply stop using contraception.
- What is osteopenia, and what should be done about it?
Because the term “osteopenia” is not useful as a diagnosis and can actually be harmful, I am on a personal crusade to eliminate it from the bone density lexicon.
- Abdominal aortic aneurysms: What we don’t seek, we won’t find
We don’t find abdominal aortic aneurysms as often as we should. In some patients we should consider ultrasonographic screening.
- In rebuttal: Osteopenia is a useful diagnosis
Eliminating the term “osteopenia” would foster complacency and a do-nothing attitude toward a serious and common disease.
- Severe chest pain in a 32-year-old man
His electrocardiogram shows ST-segment elevation in leads I, II, aVF, and V5 and V6, but no reciprocal changes. What is the diagnosis?
- Diabetes insipidus: Diagnosis and treatment of a complex disease
Diabetes insipidus can be life-threatening, and the treatment depends on the cause in the individual patient.
- Should we screen for abdominal aortic aneurysms?
The short answer is yes, but only in the right patients.
- Contrast-induced nephropathy: How it develops, how to prevent it
The evidence and our recommendations for using hydration, N-acetylcysteine, sodium bicarbonate, theophylline, and hemofiltration.

