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Review

Autosomal dominant polycystic kidney disease and the heart and brain

Vinod Krishnappa, MBBS, Poornima Vinod, MD, Divya Deverakonda and Rupesh Raina, MD, FAAP, FACP, FASN, FNKF
Cleveland Clinic Journal of Medicine June 2017, 84 (6) 471-481; DOI: https://doi.org/10.3949/ccjm.84a.16107
Vinod Krishnappa
Department of Nephrology, Cleveland Clinic Akron General/Akron Nephrology Associates, Akron, OH
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Poornima Vinod
Cleveland Clinic Akron General, Akron, OH
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Divya Deverakonda
Biomolecular Science, NYU Tandon School of Engineering, Brooklyn, NY
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Rupesh Raina
Consultant Nephrologist, Adult-Pediatric Kidney Disease/Hypertension, Department of Nephrology, Cleveland Clinic Akron General and Akron Children’s Hospital, Akron, OH
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    FIGURE 1

    Pathogenesis and treatment of hypertension and left ventricular hypertrophy in ADPKD.

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    FIGURE 2
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    FIGURE 3

    Screening for intracranial aneurysm in autosomal dominant polycystic kidney disease.

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    TABLE 1

    Cardiovascular complications of autosomal dominant polycystic kidney disease

    Hypertension
    Cardiac complications
    Left ventricular hypertrophy
    Valvular complications
     Mitral valve prolapse
     Mitral regurgitation
     Aortic regurgitation
     Tricuspid regurgitation
     Tricuspid valve prolapse
    Atrial myxoma
    Pericardial effusion
    Coronary artery disease
     Atherosclerosis
     Coronary artery aneurysm
     Coronary artery dissection
    Aneurysm
    Intracranial
    Popliteal and splenic arteries
    Dissection
    Aorta
    Internal carotid artery
    Vertebral arteries
    Iliac arteries
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Cleveland Clinic Journal of Medicine: 84 (6)
Cleveland Clinic Journal of Medicine
Vol. 84, Issue 6
1 Jun 2017
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Autosomal dominant polycystic kidney disease and the heart and brain
Vinod Krishnappa, Poornima Vinod, Divya Deverakonda, Rupesh Raina
Cleveland Clinic Journal of Medicine Jun 2017, 84 (6) 471-481; DOI: 10.3949/ccjm.84a.16107

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Autosomal dominant polycystic kidney disease and the heart and brain
Vinod Krishnappa, Poornima Vinod, Divya Deverakonda, Rupesh Raina
Cleveland Clinic Journal of Medicine Jun 2017, 84 (6) 471-481; DOI: 10.3949/ccjm.84a.16107
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  • Article
    • ABSTRACT
    • ADPKD ACCOUNTS FOR 10% OF END-STAGE RENAL DISEASE
    • HYPERTENSION IN ADPKD
    • MANAGING HYPERTENSION IN ADPKD
    • LEFT VENTRICULAR HYPERTROPHY IN ADPKD
    • MANAGING LEFT VENTRICULAR HYPERTROPHY IN ADPKD
    • INTRACRANIAL ANEURYSM IN ADPKD
    • SCREENING FOR INTRACRANIAL ANEURYSM
    • CARDIAC VALVULAR ABNORMALITIES IN ADPKD
    • CORONARY ARTERY DISEASE AND ANEURYSM IN ADPKD
    • ATRIAL MYXOMA, CARDIOMYOPATHY, AND PERICARDIAL EFFUSION IN ADPKD
    • EMERGING THERAPIES AND TESTS
    • REFERENCES
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