Table of Contents
From the Editor
- Quality, frailty, and common senseIdeal management of the frail elder with severe congestive heart failure is not always a matter of devices and drugs. 
Im Board Review
- A 25-year-old man with very high alkaline phosphataseHe has generalized malaise, a palpably enlarged liver, and an alkaline phosphatase level of 1,307 U/L. What is the cause? 
The Clinical Picture
- A less common source of dyspnea in sclerodermaA 48-year-old man with scleroderma reports progressive shortness of breath, fatigue, and melena over the past month. What is the link? 
- Presumed premature ventricular contractionsThe electrocardiogram shows what appear to be premature ventricular contractions. But are they? 
Im Board Review
- A 54-year-old woman with pancytopeniaHer red blood cell, white blood cell, and platelet counts are all low. What is the cause? 
Review
- Essential tremor: Choosing the right management plan for your patientSuccessful management entails excluding secondary causes, carefully selecting drug therapy, and, in severe resistant or atypical cases, referring to a specialist. 
Current Drug Therapy
- Bioidentical hormone therapy: Clarifying the misconceptionsMany women are turning to bioidentical hormone therapy on the basis of misconceptions, which we hope to clarify. 
Review
- Heart failure in frail, older patients: We can do ‘MORE’A comprehensive approach is necessary in managing heart failure in frail older adults. Physicians need to draw from the fields of internal medicine, geriatrics, and cardiology. 
Departments
- The negative U wave in the setting of demand ischemia (August 2011)Readers comment on negative U waves (August 2011) and on dabigatran (October 2011). 
- Dabigatran (October 2011)Readers comment on negative U waves (August 2011) and on dabigatran (October 2011). 




