Dermatology

  • Hyperpigmentation as a clue to Addison disease
    Yusuke Hirota, MD, PhD and Takaya Matsushita, MD, PhD
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 498-499; DOI: https://doi.org/10.3949/ccjm.89a.21082

    The 66-year-old woman presented with fatigue, loss of appetite, and hyperpigmentation of the tongue, soft palate, buccal mucosa, lower lip, fingers, and nail beds.

  • Circulating lipids are not all bad: An LDL mimic that may be only skin deep
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine August 2022, 89 (8) 422-423; DOI: https://doi.org/10.3949/ccjm.89b.08022

    Although lipoprotein-X separates out by density in the low-density lipoprotein (LDL) fraction and thus may appear as LDL in the laboratory report, it is biologically unique.

  • Xanthomas: Differentiating atherogenic from nonatherogenic
    Vy Mai, MD and Hossein Akhondi, MD
    Cleveland Clinic Journal of Medicine August 2022, 89 (8) 429-431; DOI: https://doi.org/10.3949/ccjm.89a.21088

    The patient had tendinous xanthomas on the dorsal joints of the hand and eruptive xanthomas on the buttock, as well as xanthoma striatum palmare on the volar aspect of the hand.

  • Mondor disease of the breast
    Toshiyuki Yamaguchi, MD
    Cleveland Clinic Journal of Medicine July 2022, 89 (7) 371-372; DOI: https://doi.org/10.3949/ccjm.89a.21097

    A 43-year-old woman had 2 weeks of pain and skin tightness over the right breast. Ultrasonography revealed a noncompressible, dilated, subcutaneous vein without flow.

  • Atypical erythema as a clinical presentation of tinea incognito
    Ana Ravić Nikolić, MD, PhD and Gordana Ristić
    Cleveland Clinic Journal of Medicine June 2022, 89 (6) 295-296; DOI: https://doi.org/10.3949/ccjm.89a.21091

    The lesions were originally diagnosed as contact allergic dermatitis and treated with topical corticosteroids, but culture revealed Trichophyton rubrum.

  • Skin-colored papules on the cheeks, acrochordons on the axillae
    Irene López Riquelme, MD, María Ayala Blanca, MD, PhD and Elisabeth Gómez Moyano, MD, PhD
    Cleveland Clinic Journal of Medicine June 2022, 89 (6) 297-299; DOI: https://doi.org/10.3949/ccjm.89a.21087

    Biopsy revealed dermal follicular structures surrounded by a perifollicular fibrous sheath and a densely fibrous stroma, consistent with a fibrofolliculoma.

  • Spider nevi secondary to alcoholic chronic liver disease
    Mohamed Adam Ali, MBBS, BSc, FHEA
    Cleveland Clinic Journal of Medicine June 2022, 89 (6) 301-302; DOI: https://doi.org/10.3949/ccjm.89a.21064

    The lesions blanched when pressure was applied centrally and refilled from the center outward when pressure was released.

  • Pigmented lesion on nail bed: Pseudo-Hutchinson sign
    Yahya Daneshbod, MD, Majid Akrami, MD, Sara Fanaee, MD, Komeil Mirzaei Baboli, MD and Hadi Mirfazaelian, MD
    Cleveland Clinic Journal of Medicine June 2022, 89 (6) 303-304; DOI: https://doi.org/10.3949/ccjm.89a.21070

    The discoloration had been present since the patient was 14, and it had not changed in appearance.

  • Spotty skin pigmentation in Carney complex
    Azusa Sano, MD, Yosuke Ono, MD, PhD, Naoya Fujita, MD and Yuji Tanaka, MD, PhD
    Cleveland Clinic Journal of Medicine June 2022, 89 (6) 307-308; DOI: https://doi.org/10.3949/ccjm.89a.21069

    Characteristic skin findings and their locations can indicate underlying hereditary lentiginosis syndromes.

  • A brownish erythematous patch in the nipple-areola complex
    Irene López Riquelme, MD, Elisabeth Gómez Moyano, MD, PhD, María Ayala Blanca, PhD and Leandro Martínez Pilar, MD, PhD
    Cleveland Clinic Journal of Medicine May 2022, 89 (5) 241-242; DOI: https://doi.org/10.3949/ccjm.89a.21059

    Biopsy revealed neoplastic cells throughout the epidermis and granular layer, with abundant pale cytoplasm, intraglandular extension, and chronic inflammation in the papillary dermis.

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