Critical Care

  • Should midodrine be used as an intravenous vasopressor-sparing agent in septic shock?
    Simran Gupta, MD, Ayan Sen, MD and Aman Verma, DO
    Cleveland Clinic Journal of Medicine October 2023, 90 (10) 603-605; DOI: https://doi.org/10.3949/ccjm.90a.23040

    Research and robust data are still lacking regarding use of midodrine in this setting.

  • Which patients hospitalized with alcohol withdrawal syndrome should receive high-dose parenteral thiamine?
    Rahul B. Ganatra, MD, MPH, Anthony C. Breu, MD and Matthew V. Ronan, MD
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 22-25; DOI: https://doi.org/10.3949/ccjm.90a.22026

    The authors briefly outline risk factors for Wernicke encephalopathy and when high-dose parenteral thiamine is indicated.

  • On the horizon: Extracorporeal carbon dioxide removal
    On the horizon: Extracorporeal carbon dioxide removal
    Justin Hanks, DO, Steven Fox, MD, Omar Mehkri, MD, Laura W. Lund, PhD, Tracey Dill, RRT, Abhijit Duggal, MD, MPH, MSc and Sudhir Krishnan, MD
    Cleveland Clinic Journal of Medicine December 2022, 89 (12) 712-718; DOI: https://doi.org/10.3949/ccjm.89a.21084

    Extracorporeal carbon dioxide removal to treat hypercapnic respiratory failure has been studied in acute respiratory distress syndrome, chronic obstructive pulmonary disease, asthma, and other conditions.

  • Steroids in the acutely ill: Evolving recommendations and practice
    Stephen M. Pastores, MD, MACP, FCCP, FCCM
    Cleveland Clinic Journal of Medicine September 2022, 89 (9) 505-511; DOI: https://doi.org/10.3949/ccjm.89gr.22002

    New information has been generated with regard to what causes critical illness-related corticosteroid insufficiency, how to diagnose it, who should receive corticosteroid treatment, and what regimens to use.

  • Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Tarek Souaid, MD, Jonathan Taliercio, DO, James F. Simon, MD, MBA, Ali Mehdi, MD, MEd and Georges N. Nakhoul, MD, MEd
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 212-222; DOI: https://doi.org/10.3949/ccjm.89a.21100

    A review of the pathophysiology of anemia of chronic kidney disease, major clinical trials, and novel therapies.

  • Neuropsychiatric assessment and management of the ICU survivor
    Erin A. Dean, MD, Michelle Biehl, MD, Kathryn Bash, APRN, CNP, Jeremy Weleff, DO and Leopoldo Pozuelo, MD
    Cleveland Clinic Journal of Medicine December 2021, 88 (12) 669-679; DOI: https://doi.org/10.3949/ccjm.88a.20169

    Post-intensive care syndrome occurs in 50% to 70% of ICU survivors. The authors examine various facets of this syndrome and emphasize the role of post-ICU recovery clinics.

  • Spontaneous coronary artery dissection: Principles of management
    Nicole Pristera, MD, Pulkit Chaudhury, MD, Erik H. Van Iterson, PhD and Leslie S. Cho, MD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 623-630; DOI: https://doi.org/10.3949/ccjm.88a.20162

    Once thought to be rare, it is increasingly recognized as a common cause of acute coronary syndrome, particularly in young women.

  • Medical, ethical, and legal aspects of end-of-life dilemmas in the intensive care unit
    Jonathan Wiesen, MD, Christopher Donatelli, MD, Martin L. Smith, STD, Laurel Hyle, JD, MPH and Eduardo Mireles-Cabodevila, MD
    Cleveland Clinic Journal of Medicine September 2021, 88 (9) 516-527; DOI: https://doi.org/10.3949/ccjm.88a.14126

    Three hypothetical cases elucidate medical, ethical, and legal considerations in common end-of-life situations encountered in the ICU.

  • The obesity paradox in heart failure: What is the role of cardiorespiratory fitness?
    Asad Khan, MD, Erik H. Van Iterson, PhD and Luke J. Laffin, MD
    Cleveland Clinic Journal of Medicine August 2021, 88 (8) 449-458; DOI: https://doi.org/10.3949/ccjm.88a.20098

    What should these patients be advised about weight management and about cardiorespiratory fitness, a major factor influencing the paradox?

  • The current state of tobacco cessation treatment
    Humberto K. Choi, MD, FCCP, Jorge Ataucuri-Vargas, MD, Charlie Lin, MD and Amanda Singrey, PharmD, BCACP, CTTS
    Cleveland Clinic Journal of Medicine July 2021, 88 (7) 393-404; DOI: https://doi.org/10.3949/ccjm.88a.20099

    Behavioral interventions and pharmacotherapy increase success rates. Alternative treatments should not replace or delay the use of known effective therapies.

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