Review
Lactic acidosis: Clinical implications and management strategies
Anita J. Reddy, MD, Simon W. Lam, PharmD, FCCM, Seth R. Bauer, PharmD, FCCM and Jorge A. Guzman, MD
Cleveland Clinic Journal of Medicine September 2015, 82 (9) 615-624; DOI: https://doi.org/10.3949/ccjm.82a.14098
Anita J. Reddy
Quality Officer, Medical Intensive Care Unit, Departments of Pulmonary Medicine and Critical Care Medicine, Respiratory Institute, Cleveland Clinic; Assistant Professor, Cleve-land Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
Simon W. Lam
Department of Pharmacy, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
Seth R. Bauer
Medical ICU Clinical Specialist, Department of Pharmacy, Cleveland Clinic
Jorge A. Guzman
Director, Medical Intensive Care Unit, Department of Critical Care Medicine, Respiratory Institute, Cleveland Clinic

ABSTRACT
In hospitalized patients, elevated serum lactate levels are both a marker of risk and a target of therapy. The authors describe the mechanisms underlying lactate elevations, note the risks associated with lactic acidosis, and outline a strategy for its treatment.
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Cleveland Clinic Journal of Medicine
Vol. 82, Issue 9
1 Sep 2015
Lactic acidosis: Clinical implications and management strategies
Anita J. Reddy, Simon W. Lam, Seth R. Bauer, Jorge A. Guzman
Cleveland Clinic Journal of Medicine Sep 2015, 82 (9) 615-624; DOI: 10.3949/ccjm.82a.14098
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