Cardiology

  • Evaluation and management of orthostatic hypotension: Limited data, limitless opportunity
    Aldo J. Peixoto, MD
    Cleveland Clinic Journal of Medicine January 2022, 89 (1) 36-45; DOI: https://doi.org/10.3949/ccjm.89gr.22001

    Orthostatic hypotension is common and can have serious consequences. The author offers a systematic approach to evaluation and management.

  • Cardiac considerations in liver transplantation
    Cardiac considerations in liver transplantation
    Vikram Sharma, MD, MD(Res), Cerise Kleb, MD, Chirag Sheth, MD, Beni Rai Verma, MD, Vardhmaan Jain, MD, Ruchi Sharma, MD, MS, Parth Parikh, MD, Jacek Cywinski, MD, K. V. Narayanan Menon, MD, FAASLD, Jamak Modaresi Esfeh, MD, Bijan Eghtesad, MD, Cristiano Quintini, MD, Teresa Diago Uso, MD, Michael Z. Y. Tong, MD, Ravi Nair, MD, Ajay Bhargava, MD and Maan Fares, MD
    Cleveland Clinic Journal of Medicine January 2022, 89 (1) 46-55; DOI: https://doi.org/10.3949/ccjm.89a.21006

    Today’s transplant patients are older and more likely to have cardiac comorbidities, and effects of advanced liver disease on the circulatory system pose challenges in perioperative management.

  • SGLT-2 inhibitors are potential game-changers (for more than diabetes)
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 588-589; DOI: https://doi.org/10.3949/ccjm.88b.11021

    Data from large clinical trials and improved understanding of the biologic effects of these drugs are changing expectations for the clinical course in patients with diabetes, as well as chronic kidney disease and heart failure.

  • SGLT-2 inhibitors in heart failure: Time for broader eligibility and earlier initiation
    Enrico G. Ferro, MD, Bertram Pitt, MD and Deepak L. Bhatt, MD, MPH
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 601-606; DOI: https://doi.org/10.3949/ccjm.88a.21045

    SGLT-2 inhibitors remain vastly underused in clinical practice despite their broad cardiorenal benefits.

  • Spontaneous coronary artery dissection: Principles of management
    Nicole Pristera, MD, Pulkit Chaudhury, MD, Erik H. Van Iterson, PhD and Leslie S. Cho, MD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 623-630; DOI: https://doi.org/10.3949/ccjm.88a.20162

    Once thought to be rare, it is increasingly recognized as a common cause of acute coronary syndrome, particularly in young women.

  • Should my older adult patients take aspirin for primary prevention of cardiovascular disease?
    Robert M. Zimbroff, MD, Gina Ayers, PharmD, BCPS, BCGP and Kenneth Koncilja, MD
    Cleveland Clinic Journal of Medicine November 2021, 88 (11) 632-634; DOI: https://doi.org/10.3949/ccjm.88a.21024

    For patients age 70 and older, recent evidence shows that the harms outweigh the benefits.

  • We have a greater understanding of ‘cardiac syndrome X,’ but questions remain
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 532-533; DOI: https://doi.org/10.3949/ccjm.88b.10021

    A better understanding of angina due to ischemia and no obstructive coronary artery disease has led to recognition of coronary microvascular dysfunction in many of these patients.

  • Chest pain: The importance of serial ECGs
    Rene Jansen van Rensburg, MBChB, MD, Jason Schutte, MBChB and Thomas de Beenhouwer, MD
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 538-540; DOI: https://doi.org/10.3949/ccjm.88a.20183

    Repeat electrocardiograms in a 44-year-old man who presented with severe hypertension revealed de Winter and Wellens patterns.

  • Coronary microvascular dysfunction: Considerations for diagnosis and treatment
    Coronary microvascular dysfunction: Considerations for diagnosis and treatment
    Benita Tjoe, MD, Lili Barsky, MD, Janet Wei, MD, Bruce Samuels, MD, Babak Azarbal, MD, C. Noel Bairey Merz, MD and Chrisandra Shufelt, MD, MS
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 561-571; DOI: https://doi.org/10.3949/ccjm.88a.20140

    A review of pathophysiology, considerations for invasive and noninvasive coronary function testing, management, and remaining knowledge gaps.

  • The initial viral infection may be only part of the story
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2021, 88 (9) 476-477; DOI: https://doi.org/10.3949/ccjm.88b.09021

    We clearly see that the coronavirus elicits syndromes far afield from respiratory tissues. But a virus eliciting effects seemingly distinct from the primary infection is nothing new.

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