Allergy/Immunology

  • Trust the thyroid thermostat
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine August 2016, 83 (8) 552-553; DOI: https://doi.org/10.3949/ccjm.83b.08016

    Why do some physicians persist in regularly following the T3 and T4 levels in addition to the TSH?

  • Multiple linear subcutaneous nodules
    Gitesh U. Sawatkar, MD, Dipankar De, MD, Uma Nahar Saikia, MD and Sanjeev Handa, MD, FRCP (EDIN)
    Cleveland Clinic Journal of Medicine June 2016, 83 (6) 414-416; DOI: https://doi.org/10.3949/ccjm.83a.15058

    A 34-year-old woman has an asymptomatic swelling on her foot that has been slowly growing for 15 years.

  • Whiplash-shaped acute rash
    Lidia Maroñas-Jiménez, MD, Alejandro Lobato-Berezo, MD, Ramon Pigem, MD, Diana Menis, MD and Sara Palencia-Pérez, MD, PhD
    Cleveland Clinic Journal of Medicine June 2016, 83 (6) 417-418; DOI: https://doi.org/10.3949/ccjm.83a.15062

    The rash appeared suddenly 2 days after the patient ate Chinese food.

  • Allergen-specific IgE serologic assays define sensitization, not disease (January 2016)
    Robert G. Hamilton, PhD, DABMLI, FAAAA
    Cleveland Clinic Journal of Medicine May 2016, 83 (5) 326-327; DOI: https://doi.org/10.3949/ccjm.83c.05001

    A reader comments on serum IgE testing for allergy (January 2016).

  • Celiac disease: Managing a multisystem disorder
    Celiac disease: Managing a multisystem disorder
    Gursimran Singh Kochhar, MD, CNSC, FACP, Tavankit Singh, MD, Anant Gill, MBBS and Donald F. Kirby, MD, FACP, FACN, FACG, AGAF, CNSC, CPNS
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 217-227; DOI: https://doi.org/10.3949/ccjm.83a.14158

    This autoimmune disorder can cause symptoms that involve not only the gastrointestinal tract but also the skin and bones.

  • The microbiome in celiac disease: Beyond diet-genetic interactions
    Jose U. Scher, MD
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 228-230; DOI: https://doi.org/10.3949/ccjm.83a.15123

    Evidence points to the mix of bacteria that make the gut their home, collectively called the microbiome.

  • The intersection of obstructive lung disease and sleep apnea
    The intersection of obstructive lung disease and sleep apnea
    Sumita B. Khatri, MD, MS and Octavian C. Ioachimescu, MD, PhD
    Cleveland Clinic Journal of Medicine February 2016, 83 (2) 127-140; DOI: https://doi.org/10.3949/ccjm.83a.14104

    Many patients who have chronic obstructive pulmonary disease or asthma also have obstructive sleep apnea, and vice versa.

  • Serum allergen-specific IgE testing: How much is too much?
    Cheryl K. Lau, PhD and Christopher Naugler, MD, CCFP, FCFP, FRCPC
    Cleveland Clinic Journal of Medicine January 2016, 83 (1) 21-24; DOI: https://doi.org/10.3949/ccjm.83a.14125

    The Choosing Wisely campaign and others advocate against indiscriminate IgE testing in evaluating allergy.

  • Approach to asymptomatic creatine kinase elevation
    Siamak Moghadam-Kia, MD, Chester V. Oddis, MD and Rohit Aggarwal, MD, MS
    Cleveland Clinic Journal of Medicine January 2016, 83 (1) 37-42; DOI: https://doi.org/10.3949/ccjm.83a.14120

    Standard cutoffs may be too low. First, repeat the test after 7 days without exercise.

  • Autoantibody-mediated encephalitis: Not just paraneoplastic, not just limbic, and not untreatable
    Autoantibody-mediated encephalitis: Not just paraneoplastic, not just limbic, and not untreatable
    Adham Jammoul, MD, Yuebing Li, MD, PhD and Alexander Rae-Grant, MD
    Cleveland Clinic Journal of Medicine January 2016, 83 (1) 43-53; DOI: https://doi.org/10.3949/ccjm.83a.14112

    Suspect these syndromes in cases of unexplained seizure, encephalitis, or acute-onset psychiatric syndromes.

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