Most cited article(s)
- The effect of disease-modifying antirheumatic drugs on vaccine immunogenicity in adults
Patients can have variable responses to vaccines, depending on the vaccine and the DMARD.
- Sepsis and septic shock: Guideline-based management
Sepsis requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and control of the source of infection.
- Nonalcoholic fatty liver disease: A manifestation of the metabolic syndrome
As we get heavier, our livers get fattier. Despite an explosion of research on nonalcoholic fatty liver disease and gains in understanding its epidemiology and pathogenesis, a number of issues remain unresolved, including how to treat it.
- Fitz-Hugh-Curtis syndrome: A diagnosis to consider in women with right upper quadrant pain
Does your patient need a hearing aid? Primary care physicians—the gatekeepers of audiologic care—can play a more active role in improving the hearing of their adult patients.
- When patients on warfarin need surgery
How to manage anticoagulation in the perioperative period is controversial; we offer our approach.
- Recognizing and treating diabetic autonomic neuropathy
Strict glycemic control can slow the onset of diabetic autonomic neuropathy and sometimes reverse it. Other treatments address specific symptoms.
- Mitochondrial cytopathy in adults: What we know so far
The manifestations of mitochondrial cycopathy are remarkably diverse, and the syndromes identified so far probably represent only a few of the disorders.
- Recent trials of antioxidant therapy: What should we be telling our patients?
Evidence does not support the indiscriminate use of vitamins A, C, or E or beta carotene to prevent or reduce cardiovascular disease.

