Initial antibiotic therapy for community-acquired pneumonia
| Outpatients without comorbiditiesa |
| Amoxicillin |
| Or doxycycline |
| Or a macrolide |
| Outpatients with comorbidities |
| Combination therapy: |
| Amoxicillin/clavulanate or a cephalosporin |
| Plus a macrolide or doxycycline |
| Or monotherapy with a fluoroquinolone |
| Patients on a medical floor |
| A fluoroquinolone |
| Or a combination of a beta-lactam plus a macrolide |
| Intensive care patients |
| A beta-lactam |
| Plus either a macrolide or a fluoroquinolone |
| Add coverage as needed for: |
| Methicillin-resistant Staphylococcus aureus (MRSA) |
| Pseudomonas aeruginosa |
| Influenza A |
↵a Comorbidities include heart, lung, liver, or renal disease, diabetes mellitus, alcoholism, malignancy, and asplenia
Based on information from reference 1.