TABLE 2

IgE-mediated vs non–IgE-mediated food allergy

Factors consistent with IgE-mediated allergy
Onset within 2 hours of ingestion
Resolution within 12 hours
Vomiting, diarrhea, gastrointestinal pain
Symptoms of anaphylaxis (urticaria, angioedema, pruritus, cardiovascular collapse)
Acute wheezing, coughing, stridor
Factors consistent with non–IgE-mediated allergy or food intolerance
Onset hours or days after ingestion
Resolution after more than 12 hours; days
Nonspecific symptoms (diarrhea, bloody stool, food refusal, colicky pain)
Symptoms mainly associated with digestive system
  • Compiled from information in references 10 and 11.