IgE-mediated vs non–IgE-mediated food allergy
Factors consistent with IgE-mediated allergy |
Onset within 2 hours of ingestion |
Resolution within 12 hours |
Vomiting, diarrhea, gastrointestinal pain |
Symptoms of anaphylaxis (urticaria, angioedema, pruritus, cardiovascular collapse) |
Acute wheezing, coughing, stridor |
Factors consistent with non–IgE-mediated allergy or food intolerance |
Onset hours or days after ingestion |
Resolution after more than 12 hours; days |
Nonspecific symptoms (diarrhea, bloody stool, food refusal, colicky pain) |
Symptoms mainly associated with digestive system |
Compiled from information in references 10 and 11.