Southern tick-associated rash illness
| Pathogen:Unknown |
| Tick vector: Amblyomma americanum |
| Geographic distribution: Southeastern, southcentral, mid-Atlantic, and midwestern regions |
| Classic presentation: Fever, headache, fatigue, myalgia, erythema migrans rash (similar to Lyme disease) |
| Diagnosis: No diagnostic tests are available since the pathogen is unknown; diagnosis based on symptoms, geographic location, and possibility of a tick bite; a known tick bite by A americanum is helpful in distinguishing from Lyme disease. |
| Treatment: Doxycycline is often given, though it is unknown whether antibiotics are necessary or beneficial |