Anti-influenza outpatient treatments
| Treatments | Who | When | How | Clinical considerations |
|---|---|---|---|---|
| Influenza treatment: oseltamivir | Adults and children from birth | As soon as possible; ideally begin within 2 days of symptom onset | Taken at home orally | For persons at high risk ofcomplications,a initiate as soon as possible, even if > 2 days since symptom onset Renal dosing if creatinine clearance is < 60 mL/min |
| Influenza prevention after exposureb: oseltamivir | Adults and children from 3 months of age at very high risk for influenza complicationsa | Start as soon as possible after exposure | Taken at home orally | Prophylaxis and treatment dosing differ—refer to your institutional guideline Renal dosing if creatinine clearance is < 60 mL/min |
↵a Adults ≥ 65 years, people who are pregnant or post partum (within 2 weeks after delivery), residents of long-term care facilities, non-Hispanic Black persons, Hispanic or Latino persons, American Indians and Alaska natives, persons with body mass index ≥ 40 kg/m2, and individuals with certain chronic medical conditions (eg, pulmonary, cardiovascular, endocrine [eg, diabetes mellitus], renal, hepatic, hematologic, metabolic, neurologic, human immunodeficiency virus, malignancy), or those receiving immunosuppressive medications.
↵b Contact within the past 48 hours with a confirmed or suspected case.
Information from reference 22.