TABLE 2

When to stop cervical cancer screening in average-risk patients

Age > 65 years, if…After hysterectomy, if…
Patient is asymptomatic, andTotal hysterectomy (removal of the cervix) was performed,a and
Has no history of CIN2 or worse in the past 25 years, andHysterectomy was performed for benign indication, and
Has undergone adequate prior screening:
  • 3 consecutive negative cytology results in past 10 years with most recent within 3 years, or

  • 2 consecutive negative HPV test results in past 10 years with most recent within 5 years

There is no history of high-grade precancerous lesion (eg, CIN2 or worse) in the past 25 years or history of HPV-related lower genital tract cancer
  • a Patients who have undergone a hysterectomy and retained the cervix (subtotal or supracervical hysterectomy) should continue screening per guidelines for average- or high-risk screening, as clinically appropriate.

  • CIN2 = cervical intraepithelial grade 2; HPV = human papillomavirus

  • Based on information in references 12 and 13.