Recommended susceptibility-based Helicobacter pylori eradication therapy after failure of empiric therapy
| Susceptibility testing results | Recommended regimen |
|---|---|
| Clarithromycin-susceptible | Clarithromycin triple therapy for 14 days |
| Clarithromycin-resistant, metronidazole-susceptible | Metronidazole triple therapy for 14 days |
| Clarithromycin- and metronidazole-resistant, levofloxacin-susceptible | Preferred: empiric therapy with bismuth quadruple therapy for 14 days Alternative: levofloxacin triple therapy for 14 daysa |
↵a If levofloxacin triple therapy is selected and fails, bismuth quadruple therapy is the next step.
Based on information from reference 15.