TABLE 2

Clinical presentation and associated symptoms in postural orthostatic tachycardia syndrome

Cardiovascular symptomsOrthostatic intolerance, orthostatic tachycardia, palpitations, dizziness, lightheadedness, presyncope, syncope, exercise intolerance, dyspnea, chest pain, acrocyanosis, Raynaud phenomenon, venous pooling, limb edema
Noncardiovascular symptoms
GeneralDeconditioning, fatigue, heat intolerance, fever
Nervous systemHeadache, migraine, cognitive impairment, “brain fog,” difficulty concentrating, tremulousness, photophobia, phonophobia, blurred vision, neuropathic pain, sleep disorder, involuntary movements
MusculoskeletalMuscle fatigue, weakness, pain
GastrointestinalNausea, bloating, dysmotility, gastroparesis, diarrhea, constipation, pain, weight loss, irritable bowel syndrome
RespiratoryShortness of breath, hyperventilation, bronchial asthma
UrogenitalBladder dysfunction, polyuria, nocturia, urgency, frequency
SkinRash, erythema, petechiae, telangiectasias, diaphoresis, flushing, pallor, dry eyes, dry mouth, sudomotor dysregulation (hyperhidrosis, hypohidrosis, anhidrosis)
PsychiatricAnxiety, depression, panic attacks, suicidal ideation, somatic hypervigilance, catastrophizing personality
  • Based on information in reference 1.