TABLE 2

Differential diagnosis for thrombocytopenia

Disease	Thrombocytopenia	Hemolysis^a	ADAMTS13	PT/PTT	Fibrinogen	D-dimer
Thrombotic thrombocytopenic purpura	Yes	Yes	Low	Normal	Normal	Normal
Hemolytic uremic syndrome	Yes	Yes	Normal	Normal	Normal	Normal
Disseminated intravascular coagulation	Yes	Yes	Normal	Prolonged	Low	High
Immune thrombocytopenic purpura	Yes	No	Normal	Normal	Normal	Normal

↵a Anemia, increased lactate dehydrogenase, decreased haptoglobin, increased reticulocyte count, increased unconjugated bilirubin.
ADAMTS13 = a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13; PT/PTT = prothrombin time and partial thromboplastin time