Dosing of antifibrinolytic agents
| Tranexamic acid | 1–1.5 g orally every 8–12 hours for duration of bleeding |
| 10-20 mg/kg intravenous (IV) bolus followed by 10 mg/kg IV every 6–8 hours for major bleeding, hemophilic bleeding, or after major trauma | |
| Longer intervals for renal insufficiency | |
| Epsilon-aminocaproic acid | 3 g orally 3–4 times per day |
| 2 g IV every 6 hours or 1 g IV every hour, depending on the urgency | |
| Desmopressin | 0.3 μg/kg subcutaneously |
| 0.3 μg/kg IV in 50 mL of normal saline over 15–30 minutes | |
Information from reference 17.