TABLE 1

Approved indications for direct oral anticoagulants

	Nonvalvular atrial fibrillation	Treatment of deep vein thrombosis or pulmonary embolism	Prevention of deep vein thrombosis in total knee replacement	Prevention of deep vein thrombosis in total hip replacement	Prevention of deep vein thrombosis in medically ill	Coronary artery disease or peripheral artery disease
Apixaban	Yes	Yes	Yes	Yes	No	No
Betrixaban	No	No	No	No	Yes	No
Dabigatran	Yes	Yes	No	Yes	No	No
Edoxaban	Yes	Yes	No	No	No	No
Rivaroxaban	Yes	Yes	Yes	Yes	No	Yes