Comparison of MIS-C and Kawasaki disease in children
| MIS-C | Kawasaki disease | |
|---|---|---|
| Median age, year (IQR) | 9 (5.7-14) | 2.7 (1.4-4.7) |
| High-risk population | African American, Hispanic, Afro-Caribbean | Asian |
| Gastrointestinal symptoms | +++ | + |
| Shock | ++ | + |
| Low ejection fraction | ↓↓ | Normal or ↓ |
| Coronary abnormality | + | ++ |
| Intensive care support | + | ++ |
| White blood cell | ↑↑ | ↑ |
| Neutrophil | ↑↑ | ↑ |
| Lymphocyte | ↓↓ | Normal |
| Platelet | ↓ | ↑↑ |
| CRP | ↑↑↑ | ↑ |
| Ferritin | ↑↑ | Normal or ↑ |
| NT-proBNP | ↑↑↑ | Normal or ↑ |
| Troponin | ↑ | Normal or ↑ |
| D-dimer | ↑↑↑ | ↑ |
CRP = C-reactive protein; IQR = interquartile range; MIS-C = multisystem inflammatory syndrome in children; NT-proBNP = N-terminal-proB-type natriuretic peptide
Adapted from references 13–16.