RT Journal Article SR Electronic T1 Why should cancer patients participate in clinical trials? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 497 OP 499 VO 65 IS 9 A2 Markman, Maurie YR 1998 UL http://www.ccjm.org/content/65/9/497.abstract AB Primary care physicians can help their cancer patients decide whether to enter a clinical trial of an experimental treatment by frankly discussing the pros and cons. Phase 1 trials pose difficult emotional issues for patients and ethical issues for physicians.