PT  - JOURNAL ARTICLE
AU  - Hayden, Stephen P.
TI  - A practical approach to chronic fatigue syndrome
DP  - 1991 Mar 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 116--120
VI  - 58
IP  - 2
4099  - http://www.ccjm.org/content/58/2/116.short
4100  - http://www.ccjm.org/content/58/2/116.full
SO  - Cleve Clin J Med1991 Mar 01; 58
AB  - Chronic fatigue may have several physical causes, but a psychiatric condition is often involved. A substantial minority of patients are not diagnosed by conventional tests and do not respond to antidepressant therapy. These patients should be referred for psychiatric opinion or observed for new developments. Extensive virologic testing and unorthodox treatment approaches have no scientific basis at present. Claims of dramatic new diagnostic tests or therapy should be treated with caution because of the long history of unsuccessful attempts to categorize chronic fatigue into one diagnosis and the strong placebo effect shown in controlled trials.