RT Journal Article SR Electronic T1 Beyond disclosure: The necessity of trust in biomedical research JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP S49 OP S50 VO 74 IS 3 suppl 2 A1 Chisolm, Guy M. A1 Kahn, Jeffrey P. YR 2007 UL http://www.ccjm.org/content/74/3_suppl_2/S49.abstract AB Biomedical research is experiencing a crisis in public trust. Although the vast majority of clinical studies are conducted in an ethical fashion, public perceptions are fueled by well-publicized examples of unethical practices. Mistrust is further encouraged by the duality of the role of the clinical researcher, who is charged with both caring for patients and answering a research question. Disclosure is not adequate to fully address conflicts of interest in biomedical research; instead, efforts to protect patients’ interests and enhance trust should combine disclosure with an attempt to reduce conflicts in the first place as much as possible.