RT Journal Article
SR Electronic
T1 The Women’s Health Initiative: Implications for clinicians
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 385
OP 390
VO 75
IS 5
A1 Van Horn, Linda
A1 Manson, JoAnn E.
YR 2008
UL http://www.ccjm.org/content/75/5/385.abstract
AB The Women’s Health Initiative (WHI), the largest and longest randomized controlled study to date of the effect of dietary change on disease outcomes in postmenopausal women, failed to show that a low-fat diet prevents breast cancer, colon cancer, or cardiovascular disease. However, as the authors point out, the WHI Extension Study provides opportunities to assess whether nearly significant differences in breast cancer rates at 8 years become significant after 10 years of follow-up.