RT Journal Article
SR Electronic
T1 Key 2010 publications in behavioral medicine
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP S65
OP S68
DO 10.3949/ccjm.78.s1.11
VO 78
IS 8 suppl 1
A1 Kubzansky, Laura D.
YR 2011
UL http://www.ccjm.org/content/78/8_suppl_1/S65.abstract
AB Previous research has demonstrated an association between depression and incident coronary heart disease (CHD); in 2010, well-controlled studies and meta-analyses went beyond depression to include anxiety, anger expression, and negative affect as predictors of incident CHD. Emerging research suggests that positive emotions and resilience (including the ability to self-regulate) offer protection against CHD. New research is elucidating the pathophysiology to explain the effects of emotion and resilience on disease risk; for example, recent work has begun to consider how the relaxation response promotes resilience and found that it induces genomic changes that counter oxidative stress and associated cellular damage.