RT Journal Article SR Electronic T1 When patients on target-specific oral anticoagulants need surgery JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 629 OP 639 DO 10.3949/ccjm.81a.13168 VO 81 IS 10 A1 Anderson, Mary A1 Hassell, Kathryn L. A1 Trujillo, Toby C. A1 Wolfe, Brian YR 2014 UL http://www.ccjm.org/content/81/10/629.abstract AB The target-specific oral anticoagulants (TSOACs), eg, dabigatran, rivaroxaban, and apixaban, are changing the way we manage thromboembolic disease. At the same time, many clinicians wonder how best to manage TSOAC therapy when patients need surgery. An in-depth understanding of these drugs is essential to minimize the risk of bleeding and thrombosis perioperatively.