PT - JOURNAL ARTICLE AU - Braun, William E. TI - Advances in autosomal dominant polycystic kidney disease—2014 and beyond AID - 10.3949/ccjm.81gr.14001 DP - 2014 Sep 01 TA - Cleveland Clinic Journal of Medicine PG - 545--556 VI - 81 IP - 9 4099 - http://www.ccjm.org/content/81/9/545.short 4100 - http://www.ccjm.org/content/81/9/545.full SO - Cleve Clin J Med2014 Sep 01; 81 AB - Autosomal dominant polycystic kidney disease (ADPKD), which frequently leads to end-stage renal disease, currently has no specific drug therapies. Better understanding of its pathogenesis and recent clinical trials have led to more accurate diagnosis of the disease and its manifestations, as well as to promising new approaches to treatment.