RT Journal Article SR Electronic T1 Esophageal adenocarcinoma: A dire need for early detection and treatment JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 269 OP 279 DO 10.3949/ccjm.89a.21053 VO 89 IS 5 A1 Joseph, Abel A1 Raja, Siva A1 Kamath, Suneel A1 Jang, Sunguk A1 Allende, Daniela A1 McNamara, Mike A1 Videtic, Gregory A1 Murthy, Sudish A1 Bhatt, Amit YR 2022 UL http://www.ccjm.org/content/89/5/269.abstract AB Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Esophageal adenocarcinoma is the most common subtype of esophageal cancer in the United States, and its incidence has risen dramatically in the last few decades. Modern endoscopic and surgical techniques have significantly improved morbidity and mortality rates of patients undergoing treatment for esophageal cancer. However, most cases are diagnosed at a late stage when the prognosis is poor, emphasizing the need for an effective screening strategy. This clinical overview focuses on screening, multidisciplinary evaluation, and treatment of early esophageal adenocarcinoma.