PT  - JOURNAL ARTICLE
AU  - Kim, Alfred H.J.
AU  - Wu, Xiaobo
AU  - Atkinson, John P.
TI  - The beneficial and pathogenic roles of complement in COVID-19
AID  - 10.3949/ccjm.87a.ccc065
DP  - 2020 Oct 28
TA  - Cleveland Clinic Journal of Medicine
4099  - http://www.ccjm.org/content/early/2020/10/27/ccjm.87a.ccc065.short
4100  - http://www.ccjm.org/content/early/2020/10/27/ccjm.87a.ccc065.full
AB  - We briefly summarize the complement system and its functions in immunity and disease. We present data supporting the requirement of complement to resolve COVID-19, and discuss how complement overactivation later in severe disease could drive multiorgan damage characteristic of fatal COVID-19.