RT Journal Article
SR Electronic
T1 Glucocorticoid-induced osteoporosis: Insights for the clinician
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 417
OP 426
DO 10.3949/ccjm.87a.19039
VO 87
IS 7
A1 Hayat, Shakaib
A1 Magrey, Marina N.
YR 2020
UL http://www.ccjm.org/content/87/7/417.abstract
AB Glucocorticoids cause significant bone loss, predominantly affecting trabecular bone, with consequent fragility fractures. The risk of fractures is related to the dose and duration of glucocorticoid use, but an increased risk may be observed even at low doses and even in the first month of treatment. Steps to prevent or treat osteoporosis should be considered in all patients who take the equivalent of prednisone at a dose of 2.5 mg or more per day for 3 or more months.