Latest Articles
- ‘Blood will have blood’
Why should more patients die when hemoglobin levels are normalized with erythropoiesis-stimulating agents? It could be another case of “messing with Mother Nature.”
- Anemia of chronic kidney disease: When normalcy becomes undesirable
Several recent studies indicate that raising hemoglobin levels to the normal range with erythropoiesis-stimulating agents can be too much of a good thing, and the US Food and Drug Administration has issued a warning on the use of these drugs in renal disease.
- Thrombotic thrombocytopenic purpura: 2008 Update
This is one of the few hematologic emergencies. Untreated, most patients die, but prompt treatment allows most patients not only to survive but to recover.
- The Women’s Health Initiative: Implications for clinicians
Postmenopausal women who were randomized to follow a diet low in fat and high in fruits, vegetables, and grains did not have significantly lower rates of breast cancer, colon cancer, or cardiovascular disease. However, a long-term follow-up study is under way. What have we learned, and what are the implications for clinical practice?
- Acute facial purpura in an 82-year-old woman with a respiratory tract infection
The lesions appeared suddenly and spontaneously and were not associated with trauma. What is the most likely diagnosis?
- The painful knee: Choosing the right imaging test
The initial evaluation of acute knee pain should include plain radiography, but computed tomography is the test of choice for fractures, and magnetic resonance imaging is useful for evaluating the cartilage, menisci, and ligaments.
- A 61-year-old with bipolar disorder and cognitive impairment: Dementia or polypharmacy?
He reports poor concentration, using wrong words, forgetting names, and sleepiness. What is the cause?
- Prevention of venous thromboembolism in the orthopedic surgery patient
This supplement is based on the proceedings of a roundtable convened in Miami, FL, on December 1, 2007, by the Cleveland Clinic Center for Continuing Education and the Cleveland Clinic Journal of Medicine.