Latest Articles
- A judgment call
A young man hospitalized because of a sickle cell crisis requires a central venous line. However, after the catheter is inserted, an initial chest radiograph reveals that the tip may not be in the right place. What should be done?
Using biochemical markers of bone turnover in clinical practiceAlthough no guidelines to date recommend the widespread use of these markers in clinical practice, we believe they will eventually be accepted.
- When a quick sound bite won’t do
In the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, why did more patients die if they got intensive therapy than if they got standard therapy? In this issue of the Journal, an investigator in this trial gives his analysis.
- Which patients benefit from carotid stenting? What recent trials show
Whether carotid stenting has any advantage over carotid surgery and which patients should undergo it are still topics of study and debate.
- An update on proteinuric chronic kidney disease: The dual-goal approach
To slow the progression of proteinuric chronic kidney disease, we may need to set goals for lowering both blood pressure and urinary albumin excretion, using drugs that block the renin-angiotensin-aldosterone system at multiple sites or in higher doses. However, this dual-goal approach needs to be validated prospectively.
- Biochemical markers of bone turnover: Useful but underused
Markers tell us the risk of fracture and are useful in patient management. But will insurance pay for testing?
- A 51-year-old man with nodular lesions
He presents with a 1-year history of episodic pain, swelling, and stiffness in some of the metacarpophalangeal and proximal interphalangeal joints of his fingers. What is the most likely diagnosis?
- And then there were none? An internist’s reflections
In this issue, Dr. Thomas Lansdale eloquently expresses a common theme: medicine just isn’t that much fun anymore. We’d like to hear some solutions.
- Perioperative statins: More than lipid-lowering?
Soon, the checklist for internists seeing patients about to undergo surgery may include prescribing one of the lipid-lowering drugs called statins.
- Eosinophilic esophagitis: An increasingly recognized cause of dysphagia, food impaction, and refractory heartburn
This disease, which was not described as a distinct clinical entity until 1993, may be due to allergic and immune-mediated mechanisms similar to those of asthma and other atopic diseases.
