Latest Articles
- Noninvasive positive pressure ventilation for stable outpatients: CPAP and beyond
We discuss the different types of noninvasive positive pressure ventilation, the specific conditions in which they can be used, and the evidence supporting their efficacy in outpatients.
- Should healthy people take a multivitamin?
No. There is no scientific basis for recommending vitamin-mineral supplements to the healthy population.
- Bringing home the ‘medical home’ for older adults
We may be able to improve the care of our vulnerable older patients—and control costs—by taking their primary care to their own homes.
- Palmoplantar eruption
A 38-year-old woman with a history of episodes of arthritis presents with pustules on the palms and on the soles of her feet. What is the most likely diagnosis?
- Alzheimer disease prevention: Focus on cardiovascular risk, not amyloid?
Efforts to modify the course of Alzheimer disease have, until now, been based on altering the production or clearance of beta-amyloid. Results have been disappointing.
- Taking blood pressure: Too important to trust to humans?
The reality of blood pressure measurement is that human beings do not do it very well. The time has come to delegate this job to machines that can do it better.
- Combined reperfusion strategies in ST-segment elevation MI: Rationale and current role
In geographic areas where percutaneous coronary intervention (PCI) is not immediately available, the best strategy may be to give thrombolysis immediately and then to transfer the patient to a PCI hospital.
- Hepatitis C virus: Prevention, screening, and interpretation of assays
Patients at risk of hepatitis C virus infection should be screened for it so that they can be treated and potentially cured, or can at least avoid transmitting the disease to others.
- Interferon-gamma-release assays: Better than tuberculin skin testing?
These new blood tests overcome some of the limitations of skin testing, but converting to them poses challenges.
- Charcot neuroarthropathy: An often overlooked complication of diabetes
Suspect this condition if a patient with long-standing, poorly controlled diabetes and peripheral neuropathy develops a red, hot, swollen foot without ulceration.

