Latest Articles

  • Understanding the tests we order: Comments and an invitation
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2018, 85 (4) 257-260; DOI: https://doi.org/10.3949/ccjm.85b.04018

    Some new laboratory tests go through a life cycle, first being used by subspecialists and then by physicians everywhere.

  • Which test for CAD should be used in patients with left bundle branch block?
    Bo Xu, MBBS (Hons), Paul Cremer, MD, Wael Jaber, MD, Stuart Moir, MBBS, PhD, Serge C. Harb, MD and L. Leonardo Rodriguez, MD
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 224-230; DOI: https://doi.org/10.3949/ccjm.85a.17051

    CT angiography is the fi rst-line test in those under 65; for older patients there are SPECT and dobutamine echocardiography.

  • Alzheimer dementia: Starting, stopping drug therapy
    Luke D. Kim, MD, FACP, CMD and Ronan M. Factora, MD, FACP, AGSF
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 209-214; DOI: https://doi.org/10.3949/ccjm.85a.16080

    It is reasonable to consider discontinuing therapy when a patient has progressed to advanced dementia.

  • Hypertension in older adults: What is the target blood pressure?
    Anu Garg, MD and Barbara J. Messinger-Rapport, MD, PhD
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 193-195; DOI: https://doi.org/10.3949/ccjm.85a.17064

    Goal: systolic pressure below 130 mm Hg if the patient can take multiple medications and be followed closely.

  • Primary livedo reticularis of the abdomen
    Michael Chew, MD and Paul Aronowitz, MD
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 181-183; DOI: https://doi.org/10.3949/ccjm.85a.17047

    Livedo reticularis can be the manifestation of a wide range of conditions—or not.

  • Hemodynamically, the kidney is at the heart of cardiorenal syndrome
    Justin L. Grodin, MD, MPH
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 240-242; DOI: https://doi.org/10.3949/ccjm.85a.17126

    In heart failure, the heart and the kidneys share a rocky relationship.

  • A 67-year-old woman with bilateral hand numbness
    Sohab S. Radwan, MD, Khair M. Hamo and Ayman A. Zayed, MD, MSc, FACE, FACP
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 200-208; DOI: https://doi.org/10.3949/ccjm.85a.17026

    Her history includes type 2 diabetes mellitus, dyslipidemia, hypertension, diastolic heart failure, and thyroid surgery.

  • Deprescribing: When trying for less is more
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 179-180; DOI: https://doi.org/10.3949/ccjm.85b.03018

    We should periodically revisit the goals and rationale for all prescribed medications.

  • Methemoglobinemia in an HIV patient
    Riva Raiker, MD, William C. Lippert, MD, MPH and Romil Chadha, MD, MPH, FACP, SFHM
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 186-187; DOI: https://doi.org/10.3949/ccjm.85a.17004

    He had restarted his home dapsone prophylaxis, but his dyspnea worsened and his urine became dark.

  • Ascites from intraperitoneal urine leakage after pelvic radiation
    Tatsuya Fujikawa, MD, PhD and Yasuharu Tokuda, MD, PhD
    Cleveland Clinic Journal of Medicine March 2018, 85 (3) 188-189; DOI: https://doi.org/10.3949/ccjm.85a.17028

    Six years earlier, the patient had undergone hysterectomy and chemoradiotherapy for cervical cancer.

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