More articles from Symptoms to Diagnosis

  • Multiple metabolic renal manifestations of a systemic disease
    Mohamad Hanouneh, MD and Jose M. Monroy Trujillo, MD
    Cleveland Clinic Journal of Medicine March 2024, 91 (3) 155-160; DOI: https://doi.org/10.3949/ccjm.91a.23021

    A 39-year-old woman who presented with 5 days of generalized weakness and right-upper-quadrant abdominal pain was found to have an acid-base disorder, prompting evaluation for the underlying cause.

  • Hypertension and severe hyperreninemia in a young man
    Joshua M. Leisring, MD, Jason Lyou, MD, Eshetu Obole, MD and Amy A. Yau, MD
    Cleveland Clinic Journal of Medicine February 2024, 91 (2) 103-108; DOI: https://doi.org/10.3949/ccjm.91a.23055

    A 29-year-old man with blood pressure measurements of 152/118 mm Hg and 156/116 mm Hg at 2 separate clinic visits is started on combination antihypertensive therapy and undergoes evaluation for secondary causes of hypertension.

  • The drop of a pin: Accidental ingestion of a sharp foreign body
    Mina Rismani, MD, Adrian Pona, MD and Monia E. Werlang, MD
    Cleveland Clinic Journal of Medicine December 2023, 90 (12) 737-742; DOI: https://doi.org/10.3949/ccjm.90a.23029

    If endoscopic retrieval fails, conservative management may be appropriate with daily abdominal radiography.

  • Elevated aminotransferases in a 62-year-old woman
    Shahana Prakash, MD, Steven Moore, MD, PhD, Anthony Snow, MD and Kyle E. Brown, MD, FAASLD
    Cleveland Clinic Journal of Medicine November 2023, 90 (11) 669-674; DOI: https://doi.org/10.3949/ccjm.90a.23011

    Her medical history included gastroesophageal reflux disease and Sjögren syndrome. She had recently returned from travel to Malaysia.

  • Unilateral green pleural effusion in a 22-year-old woman
    Sauradeep Sarkar, MD, Utsav Shrestha, MD, Huda Elzahrany, MD and Bathmapriya Balakrishnan, BMedSci, BMBS, FCCP
    Cleveland Clinic Journal of Medicine August 2023, 90 (8) 491-498; DOI: https://doi.org/10.3949/ccjm.90a.22097

    Chills, night sweats, palpitations, and a 5-lb weight loss, preceded by 6 months of progressive dyspnea, fatigue, and reduced exercise tolerance. What is the diagnosis?

  • A 50-year-old man presents with shortness of breath
    Kaylee Watson, MD, David Wolinsky, MD, Mauricio Velez, MD and David Snipelisky, MD, FACC
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 95-101; DOI: https://doi.org/10.3949/ccjm.90a.22021

    Red flags included low voltage, normal sinus rhythm, and Q waves on electrocardiography, a history of carpal tunnel syndrome, and evidence of renal dysfunction.

  • Central vision loss in a 44-year-old woman
    Walker M. Schmidt, BS, Nirosha D. Perera, MD, Blake H. Fortes, MD, Benjamin A. Nelson, MD, Wendy M. Smith, MD and Hannah C. Nordhues, MD
    Cleveland Clinic Journal of Medicine January 2023, 90 (1) 35-41; DOI: https://doi.org/10.3949/ccjm.90a.22038

    The patient had a wide range of symptoms and comorbidities, resulting in a complicated differential diagnosis. Careful evaluation eventually led to a focus on sexually transmitted infection.

  • A 60-year-old man with prostate cancer and embolic strokes
    Neha K. Reddy, MD, MA, Christian Scherer, DO, Samuel Kessel, MD, MBA and Alejandro Moreno, MBBS, MPH, JD, MACP
    Cleveland Clinic Journal of Medicine December 2022, 89 (12) 705-711; DOI: https://doi.org/10.3949/ccjm.89a.21079

    Step-by-step evaluation of a patient with stage IV prostate cancer and embolic stroke, but no history of heart valve disease, arrhythmia, or coagulopathy.

  • Hypophosphatemia in a patient with an eating disorder
    Maxwell J. Uetz, MD, Christopher D. Knapp, MD, MPH and Samuel T. Ives, MD
    Cleveland Clinic Journal of Medicine November 2022, 89 (11) 625-629; DOI: https://doi.org/10.3949/ccjm.89a.21074

    A 32-year-old woman referred from an eating disorder treatment center reported memory difficulty, trouble concentrating, and feeling “hazy.” She was taking oral potassium phosphate 3 times daily.

  • Confusion in a 22-year-old woman, and diagnostic uncertainty
    Brian Elliott, MD, Christopher Newey, DO, MS, Katelynn Alcorn, MPH and Luke McCoy, MD
    Cleveland Clinic Journal of Medicine October 2022, 89 (10) 589-595; DOI: https://doi.org/10.3949/ccjm.89a.20176

    The patient had been complaining of gradual-onset and progressive headache and neck and back pain for 3 weeks.

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