More articles from Review

  • Hepatitis B: A strategy for evaluation and management
    Hesham M. Elgouhari, MD, Tarek I. Abu-Rajab Tamimi, MD and William Carey, MD
    Cleveland Clinic Journal of Medicine January 2009, 76 (1) 19-35; DOI: https://doi.org/10.3949/ccjm.76a.08025

    A single approach to treatment cannot be applied to all patients. Acute, adult-acquired infection rarely requires treatment, whereas treatment for chronic infection should be based on the patient’s clinical situation and test results.

  • Depression and heart disease: What do we know, and where are we headed?
    Leo Pozuelo, MD, Jianping Zhang, MD, PhD, Kathleen Franco, MD, George Tesar, MD, Marc Penn, MD, PhD and Wei Jiang, MD
    Cleveland Clinic Journal of Medicine January 2009, 76 (1) 59-70; DOI: https://doi.org/10.3949/ccjm.75a.08011

    Depression is a risk factor for new cardiac disease and has a detrimental effect in established cardiac disease. Clinicians should routinely screen for it in cardiac patients and should not hesitate to treat it.

  • Bisphosphonates and osteonecrosis of the jaw: Innocent association or significant risk?
    John J. Carey, MD, MS and Leena Palomo, DDS, MSD
    Cleveland Clinic Journal of Medicine December 2008, 75 (12) 871-879; DOI: https://doi.org/10.3949/ccjm.75a.08014

    A cause-and-effect relationship has not been established, and most of the reported cases have been in patients with cancer who were receiving much higher doses than those used in osteoporosis or Paget disease of the bone.

  • Carcinoid tumors: What should increase our suspicion?
    Gaurav Aggarwal, MD, MS, Kamil Obideen, MD and Mohammad Wehbi, MD
    Cleveland Clinic Journal of Medicine December 2008, 75 (12) 849-855; DOI: https://doi.org/10.3949/ccjm.75a.08002

    Patients often present with vague, nonspecific symptoms, and unless the primary care physician suspects that the patient has a carcinoid tumor, the appropriate testing is seldom ordered.

  • 2008–2009 Influenza update: A better vaccine match
    Sherif B. Mossad, MD
    Cleveland Clinic Journal of Medicine December 2008, 75 (12) 865-870; DOI: https://doi.org/10.3949/ccjm.75a.08088

    Last flu season, some people may have lost their faith in flu shots. In the 2008–2009 flu season, we hope to do better.

  • Parkinson disease: Not just a movement disorder
    Mayur Pandya, DO, Cynthia S. Kubu, PhD and Monique L. Giroux, MD
    Cleveland Clinic Journal of Medicine December 2008, 75 (12) 856-864; DOI: https://doi.org/10.3949/ccjm.75a.07005

    Nonmotor symptoms—sensory, autonomic, and behavioral—are common and important to recognize, as they can lead to even more serious complications and impair quality of life.

  • Hepatitis B virus infection: Understanding its epidemiology, course, and diagnosis
    Hepatitis B virus infection: Understanding its epidemiology, course, and diagnosis
    Hesham M. Elgouhari, MD, Tarek I. Abu-Rajab Tamimi, MD and William D. Carey, MD
    Cleveland Clinic Journal of Medicine December 2008, 75 (12) 881-889; DOI: https://doi.org/10.3949/ccjm.75a.07019

    Internists should be aware of the natural history of hepatitis B virus infection, a vital prerequisite to assessing disease severity and determining the need for antiviral therapy.

  • Percutaneous treatment of aortic valve stenosis
    Percutaneous treatment of aortic valve stenosis
    Inder M. Singh, MD, MS, Mehdi H. Shishehbor, DO, MPH, Ryan D. Christofferson, MD, E. Murat Tuzcu, MD and Samir R. Kapadia, MD
    Cleveland Clinic Journal of Medicine November 2008, 75 (11) 805-812;

    This less-invasive approach may become an option for patients with severe symptomatic aortic valve stenosis who cannot undergo surgery.

  • Update on constipation: One treatment does not fit all
    Amy E. Foxx-Orenstein, DO, Meredythe A. McNally, MD and Suwebatu T. Odunsi, MD
    Cleveland Clinic Journal of Medicine November 2008, 75 (11) 813-824;

    Since constipation has a variety of causes and forms, one treatment does not fit all patients. Often, the key to improvement and patient satisfaction is to understand the mechanism and the patient.

  • Skin manifestations of diabetes
    Simone Van Hattem, MD, Aart H. Bootsma, MD, PhD and H. Bing Thio, MD, PhD
    Cleveland Clinic Journal of Medicine November 2008, 75 (11) 772-787;

    Almost all diabetic patients eventually develop skin complications from the disease itself or as a side effect of glucose-lowering drugs.

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