More articles from Review
Familial hypercholesterolemia: Detect, treat, and ask about familyPatients can develop elevated LDL-C and atherosclerotic cardiovascular disease at a young age.
- Pharmacogenomics: An evolving clinical tool for precision medicine
More than 90% of patients are thought to carry at least 1 genetic variant that should prompt a change in dosing or medication.
- Sickle cell disease: A primary care update
Survival has improved, but patients still face multiorgan damage, chronic anemia, and debilitating pain crises.
- Cardio-obstetrics: Recognizing and managing cardiovascular complications of pregnancy
Pregnancy can exacerbate known cardiovascular disorders and unmask previously unrecognized problems.
- Sepsis and septic shock: Guideline-based management
Sepsis requires prompt recognition, appropriate antibiotics, careful hemodynamic support, and control of the source of infection.
- Beyond depression: Other uses for tricyclic antidepressants
The pharmacology of these drugs, their potential uses in conditions other than depression, and safety considerations.
- Gabapentin for alcohol use disorder: A good option, or cause for concern?
There is concern about the potential for abuse. Use it only as a second-line alternative, with caution.
- Vaping: The new wave of nicotine addiction
Despite perceptions that vaping is harmless and claims that it can aid in smoking cessation, risks are emerging.
- Functional heartburn: An underrecognized cause of PPI-refractory symptoms
Functional heartburn is the most common cause of failure of proton pump inhibitor therapy.
- Current management of Barrett esophagus and esophageal adenocarcinoma
Risk factors: reflux symptoms > 5 years, male sex, age > 50, white race, central obesity, and smoking.
