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Cleveland Clinic Journal of Medicine

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More articles from Cancer Diagnosis and Management

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    Chronic lymphocytic leukemia: A brief review
    John C. Krauss, MD
    Cleveland Clinic Journal of Medicine January 1998, 65 (1) 42-48;

    CLL, the most common type of leukemia, is often discovered incidentally when a routine complete blood count is performed. This paper reviews the pathology, diagnosis, and treatment of CLL.

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    Stereotactic breast biopsy: A less-invasive option
    William A. Chilcote, MD and Christine A. Quinn, MD
    Cleveland Clinic Journal of Medicine November 1997, 64 (10) 550-554;

    Percutaneous core needle biopsy, guided by digital three-dimensional x-ray imaging, offers a reasonable alternative to standard surgical biopsy.

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    Assessing and minimizing reproductive risks of cancer chemotherapy
    Maurie Markman, MD
    Cleveland Clinic Journal of Medicine October 1997, 64 (9) 465-467;

    Now that more children and young adults are surviving malignant diseases, a new problem is arising: the reproductive effects of intensive chemotherapy.

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    Inpatient management of acute leukemia
    Matt Kalaycio, MD
    Cleveland Clinic Journal of Medicine July 1997, 64 (7) 385-389;

    In treating acute leukemia, there are four medical emergencies that require immediate attention: infection, hemorrhage, hyperleukocytosis, and tumor lysis syndrome.

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    What primary care physicians should know about the toxicityof cancer chemotherapy
    Maurie Markman, MD
    Cleveland Clinic Journal of Medicine June 1997, 64 (6) 331-333;

    Although symptomatic side effects of chemotherapy reduce a patient’s quality of life, organ-system effects are potentially more serious.

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    Ethical issues in clinical trials in oncology
    Maurie Markman, MD
    Cleveland Clinic Journal of Medicine May 1997, 64 (5) 275-277;

    Ethical questions can arise in a number of situations in oncology clinical trials.

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    Calculating cancer risk: It is harder than it seems
    Iviaurie Markman, MD
    Cleveland Clinic Journal of Medicine April 1997, 64 (4) 220-221;

    Many factors make cancer risk assessment difficult, especially when determining the risk for an individual.

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    From serendipity to design: the evolution of drug development in oncology
    David M. Peereboom, MD
    Cleveland Clinic Journal of Medicine March 1997, 64 (3) 155-163;

    Although the screening of natural products remains the major method of discovering new anticancer drugs, new techniques of computer-aided drug design and combinatorial synthesis will also play a role.

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    The dilemma of evaluating and treating cancer of unknown primary site
    Maurie Markman, MD
    Cleveland Clinic Journal of Medicine February 1997, 64 (2) 73-75;

    In 5% to 10% of cancer cases, the initial presentation reflects metastases and not the primary lesion. How aggressively should one search for the tumor site?

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    When and how to use serum tumor markers in clinical practice
    Maurie Markman, MD
    Cleveland Clinic Journal of Medicine January 1997, 64 (1) 27-29;

    Clinicians have long wanted a simple test sensitive enough to detect cancer in its early stages, yet specific enough to not produce false-positive results. Unfortunately, no such ideal test exists, or is likely to.

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