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Cleveland Clinic Journal of Medicine

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    Should we still use electrocardiography to diagnose pericardial disease?
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    Acute pericarditis has a unique clinical presentation, physical findings, and electrocardiographic changes.

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    When do Raynaud symptoms merit a workup for autoimmune rheumatic disease?
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    Clues to systemic disease include prolonged and painful attacks that can cause ulceration or gangrene. Other clues are older age at onset, male sex, and asymmetric involvement.

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    Should N-acetylcysteine be used routinely to prevent contrast-induced acute kidney injury?
    Senthil K. Sivalingam, MD, Mini V. Hariharan, MBBS, Gregory L. Braden, MD and Benjamin J. Freda, DO
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    Should I order an anti-CCP antibody test to diagnose rheumatoid arthritis?
    Nilanjana Bose, MD and Leonard H. Calabrese, DO
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    This test is highly specific, though it may be redundant for a patient who has documented rheumatoid arthritis and who is seropositive for rheumatoid factor.

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    Should target natriuretic peptide levels be used for outpatient management of chronic heart failure?
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    Keji Fagbemi, MD
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    A variety of questionnaires can be used. The important thing is to be proactive about screening for this very common yet underrecognized problem.

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    The harmful effects are more theoretical than observed. On the other hand, there are also no convincing data to support the benefit of this therapy.

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