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Review

Three neglected numbers in the CBC: The RDW, MPV, and NRBC count

Jori E. May, MD, Marisa B. Marques, MD, Vishnu V.B. Reddy, MD and Radhika Gangaraju, MD
Cleveland Clinic Journal of Medicine March 2019, 86 (3) 167-172; DOI: https://doi.org/10.3949/ccjm.86a.18072
Jori E. May
Department of Medicine, University of Alabama, Birmingham
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  • For correspondence: [email protected]
Marisa B. Marques
Department of Pathology, University of Alabama, Birmingham
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Vishnu V.B. Reddy
Department of Pathology, University of Alabama, Birmingham
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Radhika Gangaraju
Department of Medicine, University of Alabama, Birmingham
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ABSTRACT

The complete blood cell count (CBC) is one of the most frequently ordered laboratory tests, but some values included in the test may be overlooked. This brief review discusses 3 potentially underutilized components of the CBC: the red blood cell distribution width (RDW), the mean platelet volume (MPV), and the nucleated red blood cell (NRBC) count. These results have unique diagnostic applications and prognostic implications that can be incorporated into clinical practice. By understanding all components of the CBC, providers can learn more about the patient’s condition.

  • Copyright © 2019 The Cleveland Clinic Foundation. All Rights Reserved.
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  1. Jori E. May, MD⇑
  1. Department of Medicine, University of Alabama, Birmingham
  1. ADDRESS:
    Jori E. May, MD, Department of Medicine, University of Alabama, 1720 2nd Avenue South, NP 2565, Birmingham, AL 35294; jemay{at}uabmc.edu
  1. Marisa B. Marques, MD
  1. Department of Pathology, University of Alabama, Birmingham
  1. Vishnu V.B. Reddy, MD
  1. Department of Pathology, University of Alabama, Birmingham
  1. Radhika Gangaraju, MD
  1. Department of Medicine, University of Alabama, Birmingham

ABSTRACT

The complete blood cell count (CBC) is one of the most frequently ordered laboratory tests, but some values included in the test may be overlooked. This brief review discusses 3 potentially underutilized components of the CBC: the red blood cell distribution width (RDW), the mean platelet volume (MPV), and the nucleated red blood cell (NRBC) count. These results have unique diagnostic applications and prognostic implications that can be incorporated into clinical practice. By understanding all components of the CBC, providers can learn more about the patient’s condition.

  • Copyright © 2019 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 86 (3)
Cleveland Clinic Journal of Medicine
Vol. 86, Issue 3
1 Mar 2019
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Three neglected numbers in the CBC: The RDW, MPV, and NRBC count
Jori E. May, Marisa B. Marques, Vishnu V.B. Reddy, Radhika Gangaraju
Cleveland Clinic Journal of Medicine Mar 2019, 86 (3) 167-172; DOI: 10.3949/ccjm.86a.18072

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Three neglected numbers in the CBC: The RDW, MPV, and NRBC count
Jori E. May, Marisa B. Marques, Vishnu V.B. Reddy, Radhika Gangaraju
Cleveland Clinic Journal of Medicine Mar 2019, 86 (3) 167-172; DOI: 10.3949/ccjm.86a.18072
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